Carotid-Cavernous Fistula

although the limitations of liver function tests are realized, it seems reasonable to conclude that the absence of any hepatic complication, in patients treated 12 to 18 months previously, suggests that H.P.C. has no marked hepatotoxic effect, in spite of its relationship to cinchophen. In fact, a careful and critical review by Hueper (1948) mentions that cinchophen, when used in the treatment of gout, was much less toxic than was commonly supposed.