Summary In a radioimmune assay under conditions of excess antigen, the binding of a mouse antiphosphorylcholine plasmacytoma protein by anti-idiotype antibody is partially inhibited by phosphorylcholine and related haptens. The effect of these haptens on the idiotype correlates with the affinity with which they are bound by the plasmacytoma protein.
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Sher et al. (1972) studied this question.