Twist-assisted proton transfer: Excited-state intramolecular proton transfer (ESIPT) in 7-(2-pyridyl)indole proceeds in a barrierless fashion and is coupled with mutual twisting of the pyridine and indole moieties. As a result, the reaction is slower in a condensed phase than in the supersonic jet-isolated molecule (1 ps vs. about 300 fs). Ultrafast radiationless deactivation of the phototautomer occurs via a conical intersection (CI).
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Nosenko et al. (2008) studied this question.
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