Key result
Atorvastatin 10 mg daily significantly improved regional left ventricular peak systolic and early diastolic velocities in patients with CAD compared to a low-fat diet (p < 0.05).
Why the study?
Does atorvastatin improve regional left ventricular systolic and diastolic functions in patients with hyperlipemia and coronary artery disease?
Does atorvastatin improve regional left ventricular systolic and diastolic functions in patients with hyperlipemia and coronary artery disease?
p-value: p=< 0.05
Atorvastatin improves regional left ventricular systolic and diastolic function in patients with CAD, an effect that appears independent of its lipid-lowering properties.
No takes yet. Share an insight, caveat, or question.
May support regional LV function benefits in CAD beyond lipids; hypothesis-generating, needs RCTs before practice change.
Qie et al. (2008) studied Hyperlipemia and coronary artery disease (n=63). Atorvastatin vs. Low-fat diet was evaluated on Regional left ventricular peak systolic velocity (VS') and early diastolic velocity (VE') (p=< 0.05). Atorvastatin 10 mg daily significantly improved regional left ventricular peak systolic and early diastolic velocities in patients with CAD compared to a low-fat diet (p < 0.05).
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