205 6. Serine is synthesized from a non-nitrogenous C3 precursor which is more closely related to an intermediate of the glycolytic pathway of glucose catabolism, possibly a triose or glyceric acid, than to pyruvate.7. The conversion of glucose, labelled in C( or in all carbon atoms, into alanine has been used to calculate the relative contribution of the glycolytic and oxidative pathways of glucose catabolism.In the intact rat none of the pyruvate appears to arise by the oxidative catabolism of glucose.We wish to thank Mr E.
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Dianzani et al. (1956) studied this question.
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