From Kemp's tricarboxylic acid the (S,S)-imide 1 and its enantiomer, as well as related imides, were synthesized. With this new chiral reagent, lithium enolates of α-monoalkylated cycloalkanones can be protonated. For instance, 2 can be transformed into 3.
No takes yet. Share an insight, caveat, or question.
Yanagisawa et al. (1994) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: