Chitosan Biopolymer Schiff Base: Preparation, Characterization, Optical, and Antibacterial Activity

Natural biopolymer used for hydrogels has attracted increasing attention in the multifaceted areas of biomedical science and engineering. The authors prepared chitosan biopolymer Schiff base by solvent exchange method using a simple aliphatic crosslinker, crotanaldehyde. The identity of Schiff base was confirmed by UV-vis and Fourier-transform infrared spectroscopy. The chitosan Schiff base was evaluated by XRD, TGA, DSC, and SEM. The microbiological screening results demonstrated the antibacterial activity of Schiff base against Escherichia coli and Staphylococcus aureus bacteria. These results suggest that the newly prepared Schiff base may open a new perspective in biomedical applications.