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A comparison of the sulphite oxidation and polarographic methods of determining oxygen‐transfer rates has been made. It has been found that the former behaves as a gas‐film‐, and the latter a liquid‐film‐controlled process. A start has been made on a rational approach to scale‐up of fermenters, based on the mass‐transfer rate and degree of turbulence. The effects of mould mycelium, anti‐foam and of surface‐active agents are discussed.
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Solomons et al. (1958) studied this question.
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