Long lasting complete response in melanoma treated by electrochemotherapy

The optimal treatment of multiple cutaneous and subcutaneous metastases of melanoma still remains unresolved. There are many different possible treatment modalities. We present a case of melanoma on the calf in which multiple cutaneous and subcutaneous metastases were treated by electrochemotherapy with cisplatin. They completely responded for eight years. After eight years two new metastatic nodules occurred and were treated by electrochemotherapy with cisplatin and again complete response was achieved. The case presents the advantages of electrochemotherapy of multiple cutaneous and subcutaneous metastases of melanoma, its relative simplicity, its minimal side effects and the possibility to treat recurrent disease as many times as needed, with long lasting complete responses.