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September 2, 2026Journal of Hospital MedicineOpen Access

Factors associated with discharge on higher respiratory support for children with tracheostomy hospitalized with bacterial tracheostomy‐associated infections: A prospective, multicenter cohort study

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Authors

KJKrystal S. JinNKNaoko KonoJCJonathan D. Cogen

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Overview

Prospective cohort study reveals higher respiratory support at discharge in children with tracheostomy infections is driven by illness severity, indicating clinical factors outweigh demographics.

Key Points

  • To identify clinical and demographic factors associated with discharge on higher respiratory support compared to baseline in pediatric patients hospitalized for bacterial tracheostomy-associated infections.
  • Prospective multicenter cohort study conducted across six freestanding children's hospitals between 2020 and 2024.
  • Evaluated 641 children aged 0–21 years across 1,180 hospitalizations using generalized linear mixed-effects regression models adjusted for patient and hospital clustering.
  • Nearly one-quarter of admissions (24.7%) resulted in discharge on higher respiratory support compared to pre-hospital baseline.
  • Discharge on higher respiratory support was significantly associated with increased oxygen requirement, escalation of chronic ventilator settings, acute ventilatory support, and longer hospital length of stay.
  • Outcomes were primarily driven by markers of acute illness severity rather than patient demographic characteristics or baseline home support factors.

Cite This Study

Jin et al. (2026) studied this question.

synapsesocial.com/papers/6a97e25ec562ede874ec668bhttps://doi.org/10.1002/jhm.70419
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