Commentary uncovers how surface immunity licenses intracellular NLR receptors via alternative RNA splicing in plants, suggesting a coordinated threshold for immune activation.
This Commentary highlights a newly uncovered layer of plant immune regulation, summarizing how surface immune signals license intracellular NLR receptors through alternative RNA splicing. This mechanism enables rapid activation of NLRs upon effector recognition, revealing that surface immunity not only amplifies defense and actively sets the threshold for intracellular immune triggering.
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Zhao et al. (2026) studied this question.
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