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September 2, 2026BMC Pregnancy and ChildbirthOpen Access

Evaluation of COVID-19 anxiety in pregnancy and its relationship with postpartum depression

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Authors

RBRazieh BinaFMFatemeh MohammadiSKShahnaz Kohan

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Overview

Prospective cohort study demonstrates that escalating third-trimester COVID-19 anxiety correlates with increased postpartum depression, highlighting the need for targeted maternal mental health...

Key Points

  • To evaluate COVID-19 anxiety levels during the third trimester of pregnancy and assess their relationship with the development of postpartum depression.
  • Prospective cohort study conducted on 206 pregnant women recruited via cluster and convenience sampling between March 2020 and August 2021.
  • Corona Disease Anxiety Scale (CDAS) was administered at 28–34 weeks and 34–40 weeks of gestation; Beck's Depression Inventory and CDAS were assessed at 4–6 weeks postpartum.
  • COVID-19 anxiety increased significantly as pregnancy progressed, rising from a mean CDAS score of 11.54 ± 7.56 at 28–34 weeks (4.7% high anxiety) to 22.05 ± 9.39 at 34–40 weeks (24.7% high anxiety).
  • Postpartum depression scores averaged 18.49 ± 10.88, with 21.4% classified as mild, 19.1% moderate, and 20.9% severe depression.
  • A significant positive correlation occurred between postpartum depression and total COVID-19 anxiety, including its psychological and physical components, across both late-pregnancy timepoints and postpartum (p < 0.001).

Cite This Study

Bina et al. (2026) studied this question.

synapsesocial.com/papers/6a97e2d9c562ede874ec734dhttps://doi.org/10.1186/s12884-026-09896-3
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