Key result
Advanced age (≥60 years) was an independent risk factor for preoperative deep vein thrombosis in patients with hip fracture, associated with a more obvious hypercoagulable state.
Why the study?
The study was conducted to analyze differences in preoperative lower extremity DVT incidence and admission blood coagulation function between younger and older adults with hip fracture to guide DVT prevention.
Does advanced age increase the incidence of preoperative DVT and hypercoagulability in patients with hip fracture?
Observational (n=505)
Does advanced age increase the incidence of preoperative DVT and hypercoagulability in patients with hip fracture?
Older adults with hip fractures have a higher incidence of preoperative DVT and a more pronounced hypercoagulable state at admission compared to younger adults.
Answers are grounded in this paper and cite their sources.
Highlights need for age-stratified DVT vigilance in hip fracture; leaves open whether targeted prophylaxis improves outcomes.
Background The objectives of this study were to analyze differences in deep vein thrombosis (DVT) incidence in both lower extremities before operation and blood coagulation function at admission in younger and older adults with hip fracture and to guide DVT prevention in these patients. Materials and Methods The 505 hip fracture patients enrolled in this research were sorted into an older adult (≥60 years) group (424 cases) and a younger adult group (81 cases) based on age. Preoperative DVT incidence in both lower extremities was analyzed. Differences in demographic characteristics, comorbidities, and preoperative DVT incidence in both lower extremities, blood coagulation function, and platelet count at admission were compared. Results Preoperative DVT incidence in both lower extremities in hip fracture patients increased with age. Compared with the younger adult group, preoperative DVT incidence in both lower extremities was higher, the ratio of women was higher, the ratio of patients with comorbidities (eg, hypertension, diabetes) was higher, fibrinogen was higher, and antithrombin III was lower in the older adult group. Conclusion Preoperative DVT incidence in both lower extremities in these patients increased with age. Compared with the younger adult group, preoperative DVT incidence was higher, hypercoagulable state was more obvious, and anticoagulant activity was weaker in the older adult group. This may be related to more patients of advanced age, a higher ratio of female patients, and more comorbidities. Advanced age (≥60 years) is the independent risk factor for preoperative DVT. [ Orthopedics . 2025;48(3):139–145.]
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Shi et al. (2025) conducted an observational in Hip fracture (n=505). Advanced age (≥60 years) vs. Younger age (<60 years) was evaluated on Preoperative DVT incidence in both lower extremities. Advanced age (≥60 years) was an independent risk factor for preoperative deep vein thrombosis in patients with hip fracture, associated with a more obvious hypercoagulable state.
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