Transparent nanopatterned plastic substrates are prepared by molding a photopolymer inside nanoporous ordered anodic alumina and subsequently etching away the mold. The array of glass-supported, index-matched nanopillars is ordered over a large area. They can serve as a platform for studying the interaction of living cells with nanotopography (see image) using quantitative optical microscopy.
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Sengupta et al. (2009) studied this question.
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