Key result
The Aip5-Bud6-Bni1 composite nucleator coordinates actin filament elongation and maintains cable thickness by binding both the formin-mediated barbed end and Aip5-associated pointed end.
Describes a novel actin nucleation mechanism involving a composite nucleator for coordinated filament elongation.
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Yansong Miao (2025) studied this question. The Aip5-Bud6-Bni1 composite nucleator coordinates actin filament elongation and maintains cable thickness by binding both the formin-mediated barbed end and Aip5-associated pointed end.
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