SUMMARY Human chorionic gonadotrophin (HCG) was assayed by biological and radioimmunological methods in 40 human term placentae. It was found that the concentration of HCG per g and per placenta was lower when the sex of the foetus was male than when it was female. This difference is significant (P < 0·005) and applies to the results obtained both in the biological and the radioimmunological assays.
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Hobson et al. (1974) studied this question.