Why the study?
Multicenter neuroimaging studies face challenges from differences in scanner hardware, pulse sequences, and reconstruction methods across sites that introduce measurement bias.
Observational
Yes
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Traveling-subject designs allow for the quantification of measurement bias introduced by different MRI scanner hardware and protocols across multiple sites.
Multicenter neuroimaging studies face the challenge that scanner hardware, pulse sequences and reconstruction methods differ substantially across sites. Such differences introduce measurement bias that can obscure or mimic biological effects. Traveling-subject (TS) designs provide a direct empirical way to quantify these biases: the same participants undergo repeated magnetic resonance imaging (MRI) sessions across multiple scanners, allowing a decomposition of variance into scanner site and subject components [1].
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Hayek et al. (2026) reported an observational. Repeated magnetic resonance imaging (MRI) sessions across multiple scanners was evaluated on Decomposition of variance into scanner site and subject components.
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