We read with interest the recent article by Chen et al., which found lower CD4+ T cells count was associated with ICU admission in patients with the coronavirus disease 2019 (COVID-19).1 Among the clinical and laboratory features of COVID-19, a number of abnormalities have been observed and described, the most prominent of which is total lymphopenia. Through routine blood analysis, a significant reduction in lymphocytes is frequently observed; however, there still lacks thoroughly research about the lymphocyte subset counts.
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Liu et al. (2020) studied this question.