A mild, efficient, and solvent‐free protocol for tetrahydropyranylation of alcohols in the presence of a catalytic amount of SnCl2 · 2H2O is reported. Simple filtration of the reaction mixture through a short silica‐gel pad gives the pure products in excellent yields. Depyranylation can also be achieved by adding methanol under similar reaction conditions.
No takes yet. Share an insight, caveat, or question.
Gogoi et al. (2007) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: