Why the study?
Does thimerosal reduce reperfusion-induced arrhythmia in a rat model of coronary ligation?
Population
73 male Sprague-Dawley rats weighing 270-285 g undergoing 6 minutes of coronary artery ligation followed by…
Comparison
Thimerosal administered 10 minutes before… vs Control (physiological saline)
Design
Preclinical
Follow-up
6 minutes of reperfusion
Authors
Loading...
Supports K-ATP modulation research in arrhythmia; hypothesis-generating only, no clinical implications yet.
Does thimerosal reduce reperfusion-induced arrhythmia in a rat model of coronary ligation?
Thimerosal reduces reperfusion-induced arrhythmias in a rat model, an effect that appears dependent on the blockade of ATP-dependent potassium channels.
Bozdoǧan et al. (2005) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: