Xanthine oxidase (XO) inhibitor was isolated from the aerial parts of Athylium mesosorum MAKINO (Aspidiaceae) and was identified as norathyriol (1, 3, 6, 7-tetrahydroxyxanthone) (1). The type of inhibition by 1 with respect to xanthine as a substrate was uncompetitive. The inhibitory activities of related xanthone derivatives towards XO were assayed.
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Noro et al. (1984) studied this question.
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