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July 28, 2023Open Access

Impact of Extended Shifts on Cerebral Oxygen Saturation and Cognitive Function in Pediatric Residents (Preprint)

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Why the study?

On-call shifts are linked to impaired cognition and alertness, but whether sleep deprivation reduces regional cerebral oxygen saturation (rScO2) was unknown.

Does sleep deprivation following 16-h nightshifts reduce cerebral oxygen saturation and cognitive function in pediatric residents?

Population

50 in-training pediatricians

Comparison

Nightshifts and continuous working without post-call day vs pre on-call baseline

Design

Prospective study

Follow-up

48-h

Key result

16-hour nightshifts among pediatric residents significantly reduced regional cerebral oxygen saturation (68.2% to 64.6%, p<0.001) and MoCA scores (28.4 to 27.7, p<0.001) at 24 hours.

Authors

PJPimchanok JunsawatNANattachai AnantasitJVJarin Vaewpanich

Discussion

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Member takes

Overview

May support limiting extended shifts in residency training; hypothesis-generating for effects on clinical performance and patient outcomes.

Study Design

Type

Observational (n=50)

Structured PICO

Does sleep deprivation following 16-h nightshifts reduce cerebral oxygen saturation and cognitive function in pediatric residents?

P
Population
50 in-training pediatricians monitored for cerebral oxygen saturation and cognitive function up to 48 hours after a 16-hour nightshift.
E
Exposure
16-h nightshifts and continuous working without post-call day (sleep deprivation)
C
Comparator
Pre on-call baseline (T0)
O
Outcome
Regional cerebral oxygen saturation (rScO2) and cognitive function (mathematical test, MoCA) at T0, T16, T24, and T48surrogate

Main Result

Absolute Event Rate: 64.6% vs 68.2%

p-value: p=<0.001

Extended 16-hour nightshifts without a post-call day cause transient reductions in cerebral oxygen saturation and cognitive function in pediatric residents.

Cite This Study

Junsawat et al. (2023) conducted an observational in Sleep deprivation (n=50). 16-hour nightshifts and continuous working vs. Pre on-call baseline was evaluated on Regional cerebral oxygen saturation (rScO2) at 24 hours from pre on-call (p=<0.001). 16-hour nightshifts among pediatric residents significantly reduced regional cerebral oxygen saturation (68.2% to 64.6%, p<0.001) and MoCA scores (28.4 to 27.7, p<0.001) at 24 hours.

synapsesocial.com/papers/6a9813d9ff0077060d8bf1adhttps://doi.org/10.2196/preprints.51349
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