There exist numerous genes disseminated by mobile elements that can confer cross-resistance to lincosamides and streptogramin A compounds in staphylococci. This study investigated the nature and means of dissemination of genes responsible for LS A resistance among 24 French clinical isolates screened for reduced susceptibility to lincomycin. The vga (A) v gene was found to be the most prevalent determinant of LS A resistance, while Tn 5406 appeared to be its exclusive gene support.
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Tessé et al. (2013) studied this question.
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