Key result
The beating heart technique during frozen elephant trunk total arch replacement yielded similar in-hospital mortality (2% vs 7%, p=0.346) and less renal replacement therapy (p=0.027).
Why the study?
The study was conducted to evaluate the beating heart technique during frozen elephant trunk total arch replacement.
Does the beating heart technique improve intraoperative times and postoperative outcomes compared to cardioplegic arrest in patients undergoing FET total arch replacement?
Cohort (n=357)
No
Does the beating heart technique improve intraoperative times and postoperative outcomes compared to cardioplegic arrest in patients undergoing FET total arch replacement?
Answers are grounded in this paper and cite their sources.
The beating heart technique during FET total arch replacement may reduce operative times and the need for postoperative renal replacement therapy compared to traditional cardioplegic arrest.
Introduction Our aim was to evaluate the beating heart technique during frozen elephant trunk (FET) total arch replacement. Methods Between 03/2013 and 01/2023, 357 patients underwent FET total arch replacement in one aortic centre. Patient characteristics, intra- and postoperative data were compared between 290 patients (81%) undergoing FET repair during cardioplegic arrest and 67 patients (19%) operated on using the beating heart technique after propensity score matching. Results After propensity score matching there were no statistically significant differences in preoperative characteristics, the underlying pathology, and regarding arterial inflow-cannulation or concomitant cardiac procedures. Aortic cross-clamp ( p = .042) and cerebral perfusion ( p = .003) times were significantly shorter in the beating heart group. Postoperative cardiac biomarkers were lower, but the difference did not reach statistical significance. In-hospital mortality was numerically lower (1 [2%] vs 4 [7%], p = .346), and the incidence of postoperative renal replacement therapy was significantly lower ( p = .027) in the beating heart group. Usage of the beating heart technique was not a significant variable in our logistic regression model for in-hospital mortality, while an acute aortic pathology was highly predictive for the outcome ( p = .006, odds ratio: 3.319). Conclusions The beating heart technique has the potential to improve postoperative outcome following FET total arch replacement. The approach may be helpful for patients with reduced left ventricular function because of shorter aortic cross-clamp times.
No takes yet. Share an insight, caveat, or question.
Berger et al. (2025) conducted a cohort in frozen elephant trunk (FET) total arch replacement (n=357). beating heart technique vs. cardioplegic arrest was evaluated on in-hospital mortality (p=0.346). The beating heart technique during frozen elephant trunk total arch replacement yielded similar in-hospital mortality (2% vs 7%, p=0.346) and less renal replacement therapy (p=0.027).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: