SUMMARY Bone sarcomas (3 osteosarcomas and 1 fibrosarcoma) developed in 4 small dogs with multiple bone infarctions. Two of the dogs were Miniature Schnauzers; the other 2 were small mixed breeds weighing less than 12 kg. All 4 dogs were males. In both Schnauzers, the osteosarcomas arose in the proximal portions of the tibias; in the 3rd dog, the osteosarcoma originated from the distal part of the radius; and in the 4th, the fibrosarcoma developed in the distal portion of the femur. Only 1 of the 4 sarcomas metastasized. In all 4 dogs, infarctions occurred in more than one bone. Radiographically, the infarcts were characterized by irregular intramedullary densities. Histologically, the bone increased in mass, and many trabeculae contained empty lacunae that were overlaid by dense basophilic and mosaic-like new bone. The causative factors in the bone infarctions and the relationship of these to the sarcomas were not determined.
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Riser et al. (1972) studied this question.