Disease Outcome Subsequent to Primary and Secondary Urogenital Infection with Murine or Human Biovars ofChlamydia trachomatis

A susceptible strain of mice infected intravaginally with the mouse pneumonitis biovar of Chlamydia trachomatis became infertile and sustained high rates of hydrosalpinx formation regardless of prior infection with a human serovar. Conversely, susceptible mice infected with human serovars remained fertile unless challenged with a homologous human serovar.