, treating peptic ulcer and gastroesophageal reflux disease. They are generally well tolerated, but side-effects occur in up to 5% of patients, mainly as headache, diarrhoea and nausea (1). Fewer than 15 articles reporting cutaneous side-effects have been published, including 2 cases of cutaneous lupus erythematosus (CLE) (2, 3). We report here 5 ad-ditional cases of subacute cutaneous lupus erythematosus (SCLE) induced or exacerbated by PPIs, with a detailed summary of 2 cases.
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Dam et al. (2008) studied this question.
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