Key result
A 74-year-old woman with undiagnosed sick sinus syndrome experienced severe bradycardia and cardiopulmonary arrest during and after general anesthesia for cerebral aneurysm clipping.
Case Report (n=1)
Undiagnosed sick sinus syndrome can lead to severe bradycardia and cardiac arrest during general anesthesia, emphasizing the need for careful preoperative evaluation of unexplained bradycardia.
Sick sinus syndrome (SSS) is an abnormality of sinus nodal impulse formation by intrinsic or extrinsic causes. Patients with SSS often are asymptomatic, or have mild or nonspecific symptoms, including dizziness, palpitations, fatigue, and confusion related to the decreased cardiac output. SSS can rarely cause conditions like syncope, congestive heart failure, thromboembolism, pulmonary edema, cardiac arrest, or sudden death. We report here on a severe bradycardia during general anesthesia for aneurysmal clipping and tachycardia-bradycardia syndrome followed by cardiac arrest postoperatively in the ICU, which was subsequently diagnosed as SSS with 24-hour Holter monitoring.
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Kim et al. (2009) conducted a case report in Sick sinus syndrome (n=1). General anesthesia (propofol and remifentanil) was evaluated. A 74-year-old woman with undiagnosed sick sinus syndrome experienced severe bradycardia and cardiopulmonary arrest during and after general anesthesia for cerebral aneurysm clipping.
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