Why the study?
Paroxysmal sympathetic hyperactivity is a rare, under-recognized complication of intracerebral hemorrhage with poorly understood pathophysiology and no standardized diagnostic or treatment guidelines.
Population
One 50-year-old male with spontaneous pontine ICH who developed PSH
Design
Case report
Key result
Multimodal therapy with bromocriptine, baclofen, and clobazam achieved partial control of sympathetic storms in a 50-year-old male with paroxysmal sympathetic hyperactivity after pontine hemorrhage.
Authors
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May inform refractory PSH management; leaves open need for controlled trials.
Case Report (n=1)
No
This case highlights the diagnostic and therapeutic challenges of paroxysmal sympathetic hyperactivity following spontaneous pontine hemorrhage, emphasizing the need for early recognition and multimodal therapy to prevent complications like rhabdomyolysis.
Lo et al. (2025) conducted a case report in Paroxysmal sympathetic hyperactivity following spontaneous pontine hemorrhage (n=1). Multimodal therapy (bromocriptine, baclofen, and clobazam) was evaluated on Control of sympathetic storms. Multimodal therapy with bromocriptine, baclofen, and clobazam achieved partial control of sympathetic storms in a 50-year-old male with paroxysmal sympathetic hyperactivity after pontine hemorrhage.