In 124 patients with femoral neck fracture and 74 aged control subjects a seasonal variation was observed in the serum concentrations of 25-hydroxyvitamin D, 24,25-dihydroxyvitamin D, and PTH. The serum PTH concentrations were maximal in winter, when the vitamin D metabolites were lowest, suggesting a secondary phenomenon.
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Lips et al. (1983) studied this question.