We studied the acidifying efficiency of a cold atmospheric pressure plasma treatment and ambient air as a working gas on lipid films. Acidification of a thin water film could be observed on plasma-treated surfaces of wool wax, pork sebum and human lipids. This pH shift was partly attributable to NO x species and to the formation of nitric acid in the upper layers of the substrates. The acidic compounds on the lipid surfaces resulted in pH shifts for up to 2 h after plasma exposure, which might be beneficial for pH-targeted therapies in dermatology.
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Helmke et al. (2009) studied this question.
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