An improved preparation of 4‐imidazoleëthanol [4‐(2‐hydroxyethyl)imidazole] (I) is described. Starting from 2‐butyne‐1,4‐diol (II), 4‐(2‐methoxyethyl)imidazole (III) has been obtained, which on cleavage with hydrobromic acid gives I in satisfactory overall yield. Prolonged heating of III in hydrobromic acid gives 4‐(2‐bromoethyl)imidazole hydrobromide.
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Bloemhoff et al. (1970) studied this question.
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