Key result
Patients with atrial fibrillation had significantly lower mean serum sodium levels compared to controls (136.0 vs 142.0 mEq/l; p=0.04).
Why the study?
Is serum sodium concentration associated with atrial fibrillation in adult emergency department patients?
Cross-Sectional (n=240)
Is serum sodium concentration associated with atrial fibrillation in adult emergency department patients?
Absolute Event Rate: 136% vs 142%
p-value: p=0.04
Lower serum sodium levels are associated with the presence of atrial fibrillation, particularly paroxysmal atrial fibrillation, in emergency department patients.
Lower sodium associated with AF in ED patients; hypothesis-generating and leaves open causal or prognostic value.
3 , Ugur Lok 2 , Hakan Topacoglu 4 Abstract Objective: Alterations in serum levels of sodium may lead to cardiac arrhythmia by affecting the membrane potentials of cardiac cells. Previous studies have documented the association between postoperative atrial fibrillation and reduction in serum magnesium level after cardiovascular surgery well. However, there is no study assessing the relationship between serum sodium concentration and atrial fibrillation. Therefore, we aimed to investigate the relationship between serum sodium concentration and atrial fibrillation. Material and Methods: The present study had a cross-sectional design. The study population included 240 cases (120 patients with atrial fibrillation and 120 controls). Patients with atrial fibrillation were compared with the control group in terms of serum sodium level. Results: The mean serum sodium level in the atrial fibrillation group was 136.0±18.3 mEq/l, while it was found to be 142.0±23.9 mEq/l (p=0.04) in the control group. The mean serum sodium level in patients with permanent atrial fibrillation was 139±14 mEq/l, whereas it was 132.0±22.5 mEq/l in patients with parox - ysmal atrial fibrillation (p=0.03). Conclusion: This study indicates that low serum sodium level might be associated with atrial fibrillation. However, to obtain accurate results, new prospective studies with more patients are needed. (JAEM 2014; 13: 131-4)
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Can et al. (2014) conducted a cross-sectional in Atrial fibrillation (n=240). Atrial fibrillation vs. Controls was evaluated on Mean serum sodium level (p=0.04). Patients with atrial fibrillation had significantly lower mean serum sodium levels compared to controls (136.0 vs 142.0 mEq/l; p=0.04).
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