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The utility of 3-oxo-N-(pyrimidin-2-yl)butanamide (1) in the synthesis of some new pyrazole, thiophene, thiazole, and 1,3,4-thiadiazole derivatives pendant to a pyrimidine ring is reported.Antimicrobial evaluation of some selected examples from the synthesized products was carried out and showed moderate activity.
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Farag et al. (2009) studied this question.
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