Key result
The implantable photonic sensor system measured arterial wall movements in vivo with sub-micron resolution, a precision of 5 µm, and a temporal resolution of 10 kHz.
A novel implantable photonic sensor enables continuous, high-resolution measurement of arterial distension in vivo, offering a new tool for researching arterial stiffness and cardiovascular hemodynamics.
May advance preclinical arterial stiffness research; leaves open human translation and safety validation.
with sub-micron resolution, a precision in the micrometer range and a temporal resolution of 10 kHz. The photonic measurement principle is based on transmission photoplethysmography with stretchable optoelectronic sensors applied directly to large systemic arteries. The presented photonic sensor system expands the toolbox of cardiovascular measurement techniques and makes these key vital parameters continuously accessible over the long-term. In the near term, this new approach offers a tool for clinical research, and as a perspective, a continuous long-term monitoring system that enables novel diagnostic methods in arteriosclerosis and hypertension research that follow the trend in quantifying cardiovascular diseases by measuring arterial stiffness and more generally analyzing pulse contours.
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Ruh et al. (2016) studied Arterial distension. Implantable photonic sensor system was evaluated on Resolution and precision of arterial distension measurement. The implantable photonic sensor system measured arterial wall movements in vivo with sub-micron resolution, a precision of 5 µm, and a temporal resolution of 10 kHz.
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