Why the study?
Are maternal exposures during the first trimester associated with an increased risk of hypoplastic left heart syndrome?
Are maternal exposures during the first trimester associated with an increased risk of hypoplastic left heart syndrome?
Maternal upper respiratory infection during the first trimester may be associated with an increased risk of hypoplastic left heart syndrome, though the study was underpowered to assess specific chemical teratogens.
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Should not alter prenatal counseling; leaves open replication in larger prospective cohorts to assess causality.
Tikkanen et al. (1994) studied this question.
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