Key result
18F-FDG PET/CT successfully staged a rare splenic pleomorphic spindle cell sarcoma, revealing innumerable intensely avid necrotic lesions in the liver and spleen.
Case Report (n=1)
No
18F-FDG PET/CT is useful for staging highly aggressive splenic pleomorphic spindle cell sarcoma, which can initially mimic benign lesions on conventional imaging.
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May support 18F-FDG PET/CT staging of rare splenic sarcomas; hypothesis-generating and requires validation in larger cohorts.
A 63-year-old male was found to have a 7.5-cm splenic mass that had imaging appearances of an atypical haemangioma on CT, ultrasound and a 99mTc-RBC scan, and he was followed conservatively with serial ultrasounds. Sixteen months later, however, the splenic lesion grew and he developed numerous new liver masses which were biopsy confirmed to be a pleomorphic spindle cell sarcoma (PSCS), formerly known as malignant fibrous histiocytoma (MFH). A staging 18F-FDG PET/CT was performed and showed innumerable, mostly necrotic hepatic and splenic masses. The patient passed away a few days after the PET/CT, before a treatment program could be implemented. The use of 18F-FDG PET/CT in the staging of splenic PSCS has not been previously described. We present the 99mTc-RBC and 18F-FDG PET/CT image characteristics of a patient with splenic PSCS.
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Makis et al. (2017) conducted a case report in Pleomorphic spindle cell sarcoma (PSCS) of the spleen (n=1). 18F-FDG PET/CT was evaluated on Staging of splenic PSCS. 18F-FDG PET/CT successfully staged a rare splenic pleomorphic spindle cell sarcoma, revealing innumerable intensely avid necrotic lesions in the liver and spleen.
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