Antimicrobial activities of sweet orange (Citrus sinensis) juice on isolated Staphylococcus aureus, Escherichia coli, Pseudomonas spp, and Klebsiella spp

Resistance to antibiotics is one of the greatest problems to the success of modern medication. Due to the emergence of multi-drug resistant bacteria, selection of effective antibiotics for suppression of microbial activity has been an incidental issue. The aim of this study is to determine the antimicrobial activities of sweet orange juice on isolated, , which were subjected to different concentrations of sweet orange juice to determine their response to the juice concentrations. 25%, 50%, & 100% concentrations were used respectively using a well-in-agar diffusion method and it was discovered that all the microorganisms were sensitive to the sweet orange juice at 100% concentration only with zones of inhibitions as follows: This shows that the juice may not be recommended as alternative for antibiotics development since it only inhibited the microbial growth at 100% concentration only, and its respective zones of inhibition were minimal or less effective.