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December 6, 2022Journal of emergency medicine, trauma & acute careOpen Access

Acute aortic dissection: Clinical characteristics and outcomes

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Why the study?

Acute aortic dissection is a serious emergency, prompting evaluation of the clinical characteristics and outcomes of medical and surgical treatments at the Ibn Al-Bitar Cardiac Centre.

Does surgery reduce mortality compared to medical treatment in patients with acute aortic dissection?

Population

33 patients admitted within 14 days after AAD symptom onset at Ibn Al-Bitar Cardiac Centre

Comparison

Medical vs surgical treatment

Design

Prospective observational study

Key result

In patients with acute aortic dissection, surgical treatment was associated with a lower mortality rate compared to medical management (37.5% vs. 62.5%).

Authors

SMSami M. MishlishAAAmjad Al-MandalawiAAAla Hadi Alwan

Discussion

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Overview

Surgery was associated with lower mortality in acute aortic dissection; hypothesis-generating and should not change practice without randomized trials.

Study Design

Type

Observational (n=33)

Multicenter

No

Structured PICO

Does surgery reduce mortality compared to medical treatment in patients with acute aortic dissection?

P
Population
33 patients (mean age 48.8 years, 18% female) admitted within 14 days of acute aortic dissection symptoms at a single center.
E
Exposure
Surgery (for complicated type B and all type A dissections)
C
Comparator
Conservative medical management (for uncomplicated type B aortic dissections)
O
Outcome
Mortality ratehard clinical

Main Result

Absolute Event Rate: 37.5% vs 62.5%

In a prospective cohort of acute aortic dissection, overall mortality was high (48.5%), with surgical treatment showing lower mortality than medical management.

Cite This Study

Mishlish et al. (2022) conducted an observational in Acute aortic dissection (n=33). Surgery vs. Medical treatment was evaluated on Mortality. In patients with acute aortic dissection, surgical treatment was associated with a lower mortality rate compared to medical management (37.5% vs. 62.5%).

synapsesocial.com/papers/6a986a36c23907cedead8e14https://doi.org/10.5339/jemtac.2022.aimco.13
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Short-term and Midterm Treatment Results in Stanford Type-B Acute Dissection Patients2019
  2. 2Endovascular Approach to Severe Acute Type B Aortic Dissection2019 · 1 citations
  3. 3Acute Stanford Type A Aortic Dissection: A Review of Risk Factors and Outcomes2023 · 14 citations
  4. 4Diagnosis and Management of Acute Type A Aortic Dissection2011 · 30 citations
  5. 5Evaluation of Acute Aortic Dissections in the Emergency Department: A Retrospective Study2021