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September 1, 1978Neuropathology and Applied Neurobiology

Ultrastructure of the Muscle Spindle in Dystrophia Myotonica. I. The Intrafusal Muscle Fibres

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Population

2 patients with dystrophia myotonica (4 spindles located in extensor indicis biopsies)

Design

Case_series

Authors

SSS.D. StranockJDJ. Newsom DavisNewYork–Presbyterian Hospital

Discussion

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Implication

Single-case finding in myotonic dystrophy warrants no practice change; extends histopathology but leaves open functional and clinical relevance.

Structured PICO

P
Population
2 patients with dystrophia myotonica (4 spindles located in extensor indicis biopsies)
O
Outcome
Ultrastructural appearance of intrafusal muscle fibres

Electron microscopy reveals severe longitudinal fragmentation of intrafusal muscle fibres and increased satellite cells in patients with dystrophia myotonica.

Cite This Study

Stranock et al. (1978) studied this question.

synapsesocial.com/papers/6a986dd6e63c287d3d9fb1f2https://doi.org/10.1111/j.1365-2990.1978.tb01351.x
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Also Consider

Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Cell populations in skeletal muscle after regeneration1970 · 30 citations
  2. 2THE RESPONSE OF MUSCLE TO STRENUOUS EXERCISE1962 · 89 citations
  3. 3Muscle Biopsy: A Modern Approach1974 · 1,356 citations