Answers are grounded in this paper and cite their sources.
Ceramidase activity could not be demonstrated in the kidney and cerebellum from a deceased patient with Farber's disease, whereas the activities of six control acid hydrolase enzymes appeared normal. This enzyme defect presumably accounts for the accumulation that has been described in two patients and may represent the biochemical basis of this disorder.
No takes yet. Share an insight, caveat, or question.
Sugita et al. (1972) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: