Key result
This review summarizes the risk of anesthetic-related neurotoxicity in young children undergoing procedures requiring sedation or general anesthesia, highlighting recent FDA warnings.
Why the study?
What is the risk of anesthetic-related neurotoxicity in young children undergoing procedures requiring sedation or general anesthesia?
What is the risk of anesthetic-related neurotoxicity in young children undergoing procedures requiring sedation or general anesthesia?
Answers are grounded in this paper and cite their sources.
This review highlights the FDA warnings regarding anesthetic-related neurotoxicity in young children and calls for careful consideration of risks versus benefits for pediatric neuroimaging.
Each year millions of young children undergo procedures requiring sedation or general anesthesia. An increasing proportion of the anesthetics used are provided to optimize diagnostic imaging studies such as magnetic resonance imaging. Concern regarding the neurotoxicity of sedatives and anesthetics has prompted the US Food and Drug Administration to change labeling of anesthetics and sedative agents warning against repeated or prolonged exposure in young children. This review aims to summarize the risk of anesthesia in children with an emphasis on anesthetic-related neurotoxicity, acknowledge the value of pediatric neuroimaging, and address this call for conversation.
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Bjur et al. (2017) conducted a review in Children requiring sedation or general anesthesia for procedures. Sedatives and anesthetics was evaluated on Anesthetic-related neurotoxicity. This review summarizes the risk of anesthetic-related neurotoxicity in young children undergoing procedures requiring sedation or general anesthesia, highlighting recent FDA warnings.
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