An iconic liquid: Investigation of the mechanism of the Beckmann rearrangement of cyclohexanone oxime to ε-caprolactam (1) in sulfuric acid or oleum has led to the conclusion that the manufacturing process for ε-caprolactam is in fact the largest-scale industrial technology that has been using an ionic liquid, caprolactamium hydrogen sulfate (2), as the reaction medium for decades.
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Fábos et al. (2008) studied this question.
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