Key result
Mildly decreased renal function (eGFR 60-69.99 mL/min/1.73 m2) in men was significantly associated with an increased risk of abnormal relative wall thickness compared to normal renal function (OR 1.68).
Why the study?
Does mildly decreased renal function associate with left ventricular geometry change in healthy adults?
Cohort (n=47,730)
No
Does mildly decreased renal function associate with left ventricular geometry change in healthy adults?
Mildly decreased renal function (eGFR 60-89) is associated with early left ventricular geometry changes (abnormal relative wall thickness) in men, suggesting a need for early cardiovascular risk management in this population.
Mild eGFR reduction was associated with abnormal LV geometry in men; hypothesis-generating for cardiorenal interactions, needs prospective confirmation before practice implications.
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Park et al. (2019) conducted a cohort in Mildly decreased renal function (n=47,730). Mildly decreased renal function (eGFR 60-69.99 mL/min/1.73 m2) vs. Normal renal function (eGFR ≥90 mL/min/1.73 m2) was evaluated on Abnormal relative wall thickness (RWT >0.42) in men (OR 1.68, 95% CI 1.28-2.21). Mildly decreased renal function (eGFR 60-69.99 mL/min/1.73 m2) in men was significantly associated with an increased risk of abnormal relative wall thickness compared to normal renal function (OR 1.68).
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