Key result
Prophylactic progesterone and personalized preconception care can reduce the incidence of preterm birth in women with a history of preterm birth or short cervical length.
Why the study?
Preterm birth is a major cause of neonatal morbidity and mortality worldwide with increasing rates, and symptomatic treatment improves neonatal outcomes but does not reduce incidence.
Do prophylactic progesterone and personalized preconception care reduce the incidence of preterm birth in at-risk women?
Do prophylactic progesterone and personalized preconception care reduce the incidence of preterm birth in at-risk women?
Answers are grounded in this paper and cite their sources.
Prophylactic progesterone and personalized preconception care are highlighted as key strategies to reduce the incidence of preterm birth.
Preterm birth (PTB), a major cause of neonatal morbidity and mortality worldwide, is increasing in many countries, particularly in low- and middle-income countries. PTB is a difficult-to-manage condition, where symptomatic treat-ment improves neonatal outcomes but does not reduce its incidence. Reduction in preterm birth can be achieved by prophylactic progesterone in women with a history of preterm birth, in those patients in whom short cervical length has been identified by routine transvaginal ultrasound, and by personalized preconception care that takes into account history and both environmental and individual risk factors.
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Tishkova et al. (2024) conducted a review in Premature birth. Prophylactic progesterone and personalized preconception care was evaluated. Prophylactic progesterone and personalized preconception care can reduce the incidence of preterm birth in women with a history of preterm birth or short cervical length.
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