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Revives interest in tumor-thrombus interactions; leaves open mechanistic validation in modern cancer cohorts.
Although Trousseau 1 was the earliest observer who noted the association between cancer and thrombosis, it was Billroth 2 who first described the presence of tumor cells within a thrombus 2 . He believed that this was a means by which tumors metastasize
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Kwaan et al. (1990) studied this question.
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