Most studies of the effect of general anesthesia on intraocular pressure have been carried out in animals. 1,2 A decrease in intraocular pressure as a result of anesthesia has usually been found. However, there has been no systematic study of the effect of general anesthesia on intraocular pressure in a large series of normal human eyes. This problem is of particular importance in the case of small children in whom intraocular pressure can only be measured under general anesthesia. This paper deals with the effect of diethyl ether, cyclopropane, vinyl ether, and thiopental sodium on intraocular pressure in a large series of patients. Material and Methods Both eyes of 70 patients undergoing short operative procedures were examined. The eyes in all cases were normal. The intraocular pressure was repeatedly measured immediately preceding the induction of anesthesia following premedication with morphine and atropine, at intervals during the course of anesthesia, and
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Walter Kornblueth (1959) studied this question.
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