Key result
The E-vita open hybrid stent-graft demonstrated 5-year survival rates of 79%, 86%, and 78% for patients with acute dissection, chronic dissection, and multisegmental aneurysmal disease, respectively.
Why the study?
Does the E-vita open hybrid stent-graft provide effective and durable repair in patients with complex pathologies of the ascending aorta, aortic arch, and descending aorta?
Observational (n=416)
Yes
Does the E-vita open hybrid stent-graft provide effective and durable repair in patients with complex pathologies of the ascending aorta, aortic arch, and descending aorta?
The E-vita open hybrid stent-graft demonstrates acceptable 5-year survival and high freedom from reoperation in patients with complex aortic pathologies.
Answers are grounded in this paper and cite their sources.
Supports hybrid stent-grafting in complex aortic disease; leaves open randomized comparisons of durability versus conventional repair.
The E-vita open hybrid stent-graft enables successful one-stage repairs of complex pathologies of the ascending aorta, aortic arch, and descending aorta. To evaluate the efficacy and durability of this treatment concept, the International E-vita open registry (IEOR) was initiated in 2008. 416 patients from 10 European centers were recruited, separated into 138 (33.2%) acute dissection cases, 142 (34.1%) chronic dissection cases, and 136 (32.7%) patients with multisegmental thoracic aneurysmal disease. In-hospital mortality was 16%, 14%, and 13% for each of the three groups, respectively, and stroke and spinal cord injury rates ranged between 5-7% and 3-9%. Survival after 5 years was 79%, 86%, and 78% for acute dissection, chronic dissection, and multisegmental aneurysmal patients, with freedom from open aortic surgery after 5 years at 96%, 94% and 82%. Findings from IEOR demonstrate the importance of the registry as an important tool for developing guidelines and frameworks in the management of this complex pathology.
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Jakob et al. (2013) conducted an observational in Complex thoracic aortic diseases (acute dissection, chronic dissection, multisegmental aneurysmal disease) (n=416). E-vita open hybrid stent-graft was evaluated on In-hospital mortality and 5-year survival. The E-vita open hybrid stent-graft demonstrated 5-year survival rates of 79%, 86%, and 78% for patients with acute dissection, chronic dissection, and multisegmental aneurysmal disease, respectively.
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