Key result
Upper hemi-sternotomy was associated with higher one-year survival compared to full sternotomy in patients undergoing mitral valve surgery (93.9% vs. 79.9%; HR 0.26; 95% CI 0.14-0.49; P<0.001).
Why the study?
It was uncertain whether patients with contraindications to right mini-thoracotomy benefit from upper hemi-sternotomy compared to standard full sternotomy for mitral valve surgery.
Does upper hemi-sternotomy improve survival and reduce complications compared to full sternotomy in patients undergoing mitral valve surgery?
Cohort (n=328)
Does upper hemi-sternotomy improve survival and reduce complications compared to full sternotomy in patients undergoing mitral valve surgery?
Hazard Ratio: 0.26 (95% CI 0.14–0.49)
Absolute Event Rate: 93.9% vs 79.9%
p-value: p=< 0.001
Upper hemi-sternotomy provides short- and mid-term survival benefits and reduces postoperative complications compared to full sternotomy in mitral valve surgery patients contraindicated for right mini-thoracotomy.
Should not yet change mitral valve surgery practice; leaves open confirmation of survival benefit in randomized trials.
Background and objectives: Certain clinical and anatomical conditions are absolute or relative contraindications for safe mitral valve surgery via the right mini-thoracotomy access. It is uncertain whether patients with these contraindications may benefit from the less invasive approach via upper hemi-sternotomy compared to standard full sternotomy. Materials and methods: Out of 2052 mitral valve surgery patients, operated from 6/04 through 2/19, 1535 were excluded due to the different criteria for eligibility to both approaches. Out of these, 350 received full sternotomy and 167 upper hemi-sternotomy. After propensity score matching, 164 pairs were analyzed for operative variables, postoperative complications and 30-day and one-year survival. Results: Upper hemi-sternotomy was associated with a survival benefit of 30 days (99.4% vs. 82.1%; p < 0.001) and one-year (93.9% vs. 79.9% p < 0.001, HR 0.26, 95% CI 0.14–0.49). Cardiopulmonary bypass and aortic cross-clamp times were comparable in both groups. Upper hemi-sternotomy resulted in less low cardiac output syndrome (18.9% vs. 31.1%; p = 0.011); ventilation time (8 vs. 13 h; p < 0.001), length of intensive care stay (1 vs. 2 days; p < 0.001) and total hospital stay (8 vs. 9 days; p < 0.001) were shorter in the upper hemi-sternotomy group. Conclusion: In patients undergoing mitral valve surgery, upper hemi-sternotomy is associated with short- and mid-term survival benefits as well as lower postoperative complication rates compared to full sternotomy. Hence, the less invasive upper hemi-sternotomy can be a valid approach in patients with contraindications for right mini-thoracotomy.
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Oezpeker et al. (2022) conducted a cohort in Mitral valve surgery (n=328). Upper hemi-sternotomy vs. Full sternotomy was evaluated on One-year survival (HR 0.26, 95% CI 0.14-0.49, p=< 0.001). Upper hemi-sternotomy was associated with higher one-year survival compared to full sternotomy in patients undergoing mitral valve surgery (93.9% vs. 79.9%; HR 0.26; 95% CI 0.14-0.49; P<0.001).
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