Key result
Pediatric patients with syncope had significantly longer QT dispersion (72 ms) compared to healthy controls (34 ms; p<0.001).
Why the study?
The authors aimed to determine whether QT dispersion can serve as a diagnostic marker for syncope type and recurrence risk in pediatric patients.
Is prolonged QT dispersion associated with pediatric syncope?
Case-Control (n=102)
Is prolonged QT dispersion associated with pediatric syncope?
Prolonged QT dispersion is significantly associated with pediatric syncope, although it does not differentiate between syncope subtypes or predict recurrence.
Answers are grounded in this paper and cite their sources.
Prolonged QT dispersion was associated with pediatric syncope; leaves open its value for subtype differentiation or recurrence prediction.
Bilici M, Fidancı-Dedeoğlu Z, Demir F, Akın A, Türe M, Balık H, Tan İ, Ertuğrul S. Prolonged QT dispersion is associated with pediatric syncope. Turk J Pediatr 2019; 61: 85-91. We aimed to find out whether QT dispersion can be used as a diagnostic marker in terms of syncope type, and recurrence risk. Fifty-two patients (28 male, 53.8%) admitted to the pediatric cardiology clinic with syncope were compared with 50 healthy controls (28 male, 56%; mean age: 13.8±2.3 years, range: 11-17 years) for QT dispersion (QTd) and other electrocardiographic findings. Gender, age, echocardiography, blood pressure while standing and sitting, electrolyte levels, liver and kidney function tests, and QTd and QTcd (calculated with corrected QT: QTc) in electrocardiography (ECG) of patients were all evaluated. Patients` ages varied between 7-17 years and the mean age at first syncope was 13.9±2.4 years. Mean follow-up duration of the patients was 10±5 months (range: 5-18 months). Mean number of syncope attacks was 2.8±2.2. QTd (72±46 ms vs. 34±14 ms) and QTcd (77±45 ms vs. 33±14 ms) values of the patients were significantly longer, compared to control group (p < 0.001). The age, gender, QTd, and QTcd values did not differ between the subtypes of syncope based on pathogenetic mechanism. Additionally, these parameters did not differ in terms of the number of syncope recurrence and tilt test. Patients` complaints reduced after cardiologic evaluation and advice regarding prevention of syncope. We think that in follow-up period, education and preventive precautions that can be taken in the daily life must be emphasized, and drug treatment can be started in unresponsive cases.
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Bilici et al. (2019) conducted a case-control in Pediatric syncope (n=102). Syncope vs. Healthy controls was evaluated on QT dispersion (QTd) (p=<0.001). Pediatric patients with syncope had significantly longer QT dispersion (72 ms) compared to healthy controls (34 ms; p<0.001).
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